Protein name:
Corticotropin-releasing factor receptor 1 (CRF-R-1;CRF-R1;CRFR-1) ;
Alternative:
Corticotropin-releasing hormone receptor 1 (CRH-R-1;CRH-R1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts (via N-terminal extracellular domain) with CRF and UCN.
Function:
Receptor for corticotropin releasing factor (CRH). Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGQRPQLRLV | KALLLLGLNP | VSTSLQDQQC | ESLSLASNVS | GLQCNASVDL |
100:
IGTCWPRSPA | GQLVVRPCPA | FFYGVRYNTT | NNGYRECLAN | GSWAARVNYS |
150:
ECQEILNEEK | KSKVHYHIAV | IINYLGHCIS | LVALLVAFVL | FLRLRSIRCL |
200:
RNIIHWNLIS | AFILRNATWF | VVQLTVSPEV | HQSNVAWCRL | VTAAYNYFHV |
250:
TNFFWMFGEG | CYLHTAIVLT | YSTDRLRKWM | FVCIGWGVPF | PIIVAWAIGK |
300:
LYYDNEKCWF | GKRPGVYTDY | IYQGPMILVL | LINFIFLFNI | VRILMTKLRA |
350:
STTSETIQYR | KAVKATLVLL | PLLGITYMLF | FVNPGEDEVS | RVVFIYFNSF |
400:
LESFQGFFVS | VFYCFLNSEV | RSAIRKRWRR | WQDKHSIRAR | VARAMSIPTS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Chicken
Mouse
ELISA Kit for Mouse CRF-R-1
ELISA Kit for Mouse CRF-R-1
ELISA Kit for Mouse CRF-R-1
ELISA Kit for Mouse CRF-R-1
CLIA Kit for Mouse CRF-R-1
CLIA Kit for Mouse CRF-R-1
CLIA Kit for Mouse CRF-R-1
CLIA Kit for Mouse CRF-R-1
Polyclonal Antibody for Mouse CRF-R-1
Polyclonal Antibody for Mouse CRF-R-1
Polyclonal Antibody for Mouse CRF-R-1
Polyclonal Antibody for Mouse CRF-R-1
Monoclonal Antibody for Mouse CRF-R-1
Monoclonal Antibody for Mouse CRF-R-1
Monoclonal Antibody for Mouse CRF-R-1
Monoclonal Antibody for Mouse CRF-R-1
Protein for Mouse CRF-R-1
Protein for Mouse CRF-R-1
Protein for Mouse CRF-R-1
Protein for Mouse CRF-R-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION
tissue :
Pituitary .
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Thompson J.
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Conroy O.
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
ILS .
strain :
ISS .
3.
"Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development."
Smith G.W.
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Aubry J.M.
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Dellu F.
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Contarino A.
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Bilezikjian L.M.
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Gold L.H.
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Neuron20:1093-1102(1998)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DLG1;TISSUE SPECIFICITY